Aiming at the difficult problem of large deformation and destruction of surrounding rock in super-kilometer deep shaft roadway, the influence of surrounding rock stress and strain evolution and rock dip angle on roadway stability was analyzed by similar simulation experiment. The time-space evolution pattern of deformation and destruction in super-kilometer deep shaft roadway is revealed. Experimental results indicate that due to the existence of rock dip angle, stress concentration appears at the two corners of roadway bottom floor. With the increase of external load, the upper left corner of arch and roadway bottom right corner are destroyed at first, and then extend to deep surrounding rock. Large scale deformation and destruction appear in surrounding rock of roadway. The stress concentration on both left and right sides of roadway intensifies. The displacement quantity of roadway surrounding rock at each position is quite different, the displacement quantity of both arch and roadway floor is larger, the displacement quantity at both sides is relatively small, the maximum deformation quantity is more than 30mm. The deformation and destruction characteristics of surrounding rock in super-kilometer deep shaft roadway can be divided into three stages: slow deformation stage, severe deformation stage and severe deformation and destruction stage. The surrounding rock of roadway produces large deformation and asymmetric destruction, and the destruction range is large. The maximum damage depth of roof and floor is up to 34mm, the surrounding rock of roadway loses its bearing capacity, and roadway space is completely closed. By applying above experimental results to engineering practice, the scheme of full section high strength prestressed bolting net support and strengthening support in special part of super-kilometer deep shaft roadway in Huafeng Coal Mine was put forward, which has achieved an ideal effect.