According to the geometrical characteristics of high-speed train bogie cabins, five design variables are extracted and six schemes are designed. The 1∶8 scaled high-speed train model with subgrade, track and bogie cabin is tested in wind tunnel, and the side slip angles of 0° and -19.8° are used in experiments. The aerodynamic drag characteristics of high-speed train corresponding to different design variables of bogie cabins are analyzed, and the drag reduction effect of each design parameter is obtained. The results show that the aerodynamic drag of the train can be reduced when the top surface of the cabin adopts the curved transition, the front and rear walls adopt inclined walls, the skirt adopts the fully enclosed skirt plate, and the longitudinal length of the inner wall is reduced. The influence of different design variables on the aerodynamic drag is analyzed, which indicates that the inner top chamfer and the longitudinal length of the inner wall have important influences on the aerodynamic drag of the train with side slip angles of 0° and -19.8°. The results have great significance for understanding the local drag reduction and the shape optimization of the train.