Deep fractured-vuggy carbonate reservoirs are rich in resources and have great potential for exploration and development. Rock physical and mechanical properties are the basis for accurate reservoir evaluation. Therefore, the reservoir of Yijianfang Formation in Manshen A well area of Fuman area in Tarim Basin was taken as the research object, and the physical and mechanical properties of reservoir rock were studied through scanning electron microscopy, casting thin section experiments, rock physical property analysis and triaxial compression experiments. The results show that the reservoir in the study area develops bioclastic, sandy beach and other limestone types, which are favorable reservoir facies belt and good reservoir. The reservoir space is mainly composed of pores and cracks, with well-developed dissolution pores, intergranular dissolution pores, micropores and microcracks, and relatively large pore throats and good connectivity. The effective porosity and permeability of the reservoir are in the range of 1.8 % ~ 5.2 % and 0.1 × 10-3 ~ 1 × 10-3μm2, respectively. The proportion of medium and high permeability reservoirs is about 65.7 %, with good overall connectivity and strong heterogeneity. The elastic modulus of rock is 38.98~61.29 GPa, and the Poisson 's ratio is 0.213-0.353. With the increase of confining pressure, the peak strength increases, but the increase gradually decreases, and the elastic modulus increases first and then decreases. The research results can provide rock physics and mechanics data basis for efficient exploration and development of deep carbonate oil and gas.